QuantiFERON-TB performance enhanced by novel Mycobacterium tuberculosis-specific antigens
نویسندگان
چکیده
منابع مشابه
QuantiFERON-TB performance enhanced by novel Mycobacterium tuberculosis-specific antigens.
One of the most significant developments in the diagnosis of tuberculosis (TB) infection has been the introduction of whole-blood based interferon-γ release assays (IGRAs) [1–3]. IGRAs, commercially available as QuantiFERON-TB Gold In-Tube test (QFT) (QIAGEN, Germantown, MD, USA) and T-SPOT.TB (Oxford Immunotec Ltd, Abingdon, UK), are based on the detection of a T-cell immune response towards R...
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BACKGROUND Currently, T-cell based gamma interferon (IFNγ) release assays (IGRAs) are acknowledged as the best methods available for the screening of latent tuberculosis infection (LTBI) and also as aid for the diagnosis of active tuberculosis (TB). To our information, the performance of these diagnostic tests has not been evaluated in Ethiopia. Therefore, the intent of this study was to evalua...
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Performance of interferon-γ (IFN-γ) release assays still needs to be improved. The data on the performance of QuantiFERON-TB Gold Plus (QFT-Plus), a new-generation of QFT assay are limited. This study evaluated the diagnostic performance of QFT-Plus, and compared to that of QuantiFERON-TB Gold In-Tube (QFT-GIT). Blood samples were collected from 162 bacteriologically confirmed tuberculosis (TB)...
متن کاملQuantiFERON TB Gold: a new method for latent tuberculosis infection.
QuantiFERON-TB Gold obtained approval in 2003 by the Food and Drug Administration as a valid tool for the diagnosis of latent tuberculosis. In this report, we evaluated its potential use in the immunological diagnosis of Mycobacterium tuberculosis infections in different groups of subjects. Our data indicate that QuantiFERON-TB Gold is specific for identifying subjects who have come into contac...
متن کاملRole of QuantiFERON-TB Gold in diagnosis of Tuberculosis
Introduction: The definitive diagnosis features can be demonstrated or mycobacteria can be isolated from the body fluids or from sputum or from gastric lavage. Various other methods, such as polymerase chain reaction are also available. It is wel and culture is difficult and time consuming and other tests are complex and technically more demanding. In this study, we correlated the results of Qu...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2015
ISSN: 0903-1936,1399-3003
DOI: 10.1183/13993003.01015-2015